Human ADH4 activation kit by CRISPRa

CAT#: GA100087

ADH4 CRISPRa kit - CRISPR gene activation of human alcohol dehydrogenase 4 (class II), pi polypeptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADH4
• Locus ID: 127
• Kit Components:

  GA100087G1, ADH4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100087G2, ADH4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100087G3, ADH4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000670, NM_001306171, NM_001306172
• Synonyms: ADH-2; HEL-S-4
• Summary: 'This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008]'