Human ADH7 activation kit by CRISPRa

CAT#: GA100090

ADH7 CRISPRa kit - CRISPR gene activation of human alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADH7
• Locus ID: 131
• Kit Components:

  GA100090G1, ADH7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100090G2, ADH7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100090G3, ADH7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000673, NM_001166504
• Synonyms: ADH4
• Summary: 'This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]'