Human ADK activation kit by CRISPRa

CAT#: GA100091

ADK CRISPRa kit - CRISPR gene activation of human adenosine kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADK
• Locus ID: 132
• Kit Components:

  GA100091G1, ADK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100091G2, ADK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100091G3, ADK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001123, NM_001202449, NM_001202450, NM_006721, NM_001369123, NM_001369124
• Synonyms: AK
• Summary: This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]