Human GRK3 activation kit by CRISPRa

CAT#: GA100110

GRK3 CRISPRa kit - CRISPR gene activation of human G protein-coupled receptor kinase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GRK3
• Locus ID: 157
• Kit Components:

  GA100110G1, GRK3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100110G2, GRK3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100110G3, GRK3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005160, NM_001362778
• Synonyms: ADRBK2; BARK2
• Summary: 'The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008]'