Human AGXT activation kit by CRISPRa

CAT#: GA100133

AGXT CRISPRa kit - CRISPR gene activation of human alanine--glyoxylate and serine--pyruvate aminotransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AGXT
• Locus ID: 189
• Kit Components:

  GA100133G1, AGXT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100133G2, AGXT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100133G3, AGXT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000030
• Synonyms: AGT; AGT1; AGXT1; PH1; SPAT; SPT; TLH6
• Summary: This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008]