Human AMD1 activation kit by CRISPRa

CAT#: GA100179

AMD1 CRISPRa kit - CRISPR gene activation of human adenosylmethionine decarboxylase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AMD1
• Locus ID: 262
• Kit Components:

  GA100179G1, AMD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100179G2, AMD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100179G3, AMD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001033059, NM_001287214, NM_001287215, NM_001287216, NM_001634, NR_109768
• Synonyms: ADOMETDC; AMD; SAMDC
• Summary: 'This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y. [provided by RefSeq, Dec 2013]'