Human APOA4 activation kit by CRISPRa

CAT#: GA100238

APOA4 CRISPRa kit - CRISPR gene activation of human apolipoprotein A4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: APOA4
• Locus ID: 337
• Kit Components:

  GA100238G1, APOA4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100238G2, APOA4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100238G3, APOA4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000482
• Synonyms: MGC142154; MGC142156
• Summary: 'Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro. [provided by RefSeq, Jul 2008]'