Human Apolipoprotein CIV (APOC4) activation kit by CRISPRa

CAT#: GA100245

APOC4 CRISPRa kit - CRISPR gene activation of human apolipoprotein C4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: APOC4
• Locus ID: 346
• Kit Components:

  GA100245G1, Apolipoprotein CIV gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100245G2, Apolipoprotein CIV gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100245G3, Apolipoprotein CIV gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001646
• Synonyms: APO-CIV; APOC-IV
• Summary: 'This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene. [provided by RefSeq, Mar 2011]'