Human ASPA activation kit by CRISPRa

CAT#: GA100319

ASPA CRISPRa kit - CRISPR gene activation of human aspartoacylase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ASPA
• Locus ID: 443
• Kit Components:

  GA100319G1, ASPA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100319G2, ASPA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100319G3, ASPA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000049, NM_001128085
• Synonyms: ACY2; ASP
• Summary: 'This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]'