Human ATP6V0B activation kit by CRISPRa

CAT#: GA100369

ATP6V0B CRISPRa kit - CRISPR gene activation of human ATPase H+ transporting V0 subunit b

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ATP6V0B
• Locus ID: 533
• Kit Components:

  GA100369G1, ATP6V0B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100369G2, ATP6V0B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100369G3, ATP6V0B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001039457, NM_001294333, NM_004047, NM_001294333.2
• Synonyms: ATP6F; HATPL; VMA16
• Summary: This gene encodes a portion of the V0 domain of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Activity of this enzyme is necessary for such varied processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]