Human KIF1A activation kit by CRISPRa

CAT#: GA100378

KIF1A CRISPRa kit - CRISPR gene activation of human kinesin family member 1A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KIF1A
• Locus ID: 547
• Kit Components:

  GA100378G1, KIF1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100378G2, KIF1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100378G3, KIF1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001244008, NM_001320705, NM_001330289, NM_001330290, NM_004321
• Synonyms: ATSV; C2orf20; HSN2C; MRD9; SPG30; UNC104
• Summary: 'The protein encoded by this gene is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]'