Human Biglycan (BGN) activation kit by CRISPRa

CAT#: GA100430

BGN CRISPRa kit - CRISPR gene activation of human biglycan

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BGN
• Locus ID: 633
• Kit Components:

  GA100430G1, Biglycan gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100430G2, Biglycan gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100430G3, Biglycan gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001711
• Synonyms: DSPG1; PG-S1; PGI; SLRR1A
• Summary: 'This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015]'