Human CXCR5 activation kit by CRISPRa

CAT#: GA100440

CXCR5 CRISPRa kit - CRISPR gene activation of human C-X-C motif chemokine receptor 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CXCR5
• Locus ID: 643
• Kit Components:

  GA100440G1, CXCR5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100440G2, CXCR5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100440G3, CXCR5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001716, NM_032966
• Synonyms: BLR1; CD185; MDR15
• Summary: 'This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]'