Human BOK activation kit by CRISPRa

CAT#: GA100462

BOK CRISPRa kit - CRISPR gene activation of human BCL2 family apoptosis regulator BOK

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BOK
• Locus ID: 666
• Kit Components:

  GA100462G1, BOK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100462G2, BOK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100462G3, BOK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032515
• Synonyms: BCL2L9; BOKL
• Summary: 'The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family. [provided by RefSeq, Sep 2011]'