Human KLF5 activation kit by CRISPRa

CAT#: GA100481

KLF5 CRISPRa kit - CRISPR gene activation of human Kruppel like factor 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KLF5
• Locus ID: 688
• Kit Components:

  GA100481G1, KLF5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100481G2, KLF5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100481G3, KLF5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001286818, NM_001730
• Synonyms: BTEB2; CKLF; IKLF
• Summary: This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]