Human Actin Regulatory Protein CAPG (CAPG) activation kit by CRISPRa

CAT#: GA100575

CAPG CRISPRa kit - CRISPR gene activation of human capping actin protein, gelsolin like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CAPG
• Locus ID: 822
• Kit Components:

  GA100575G1, Actin Regulatory Protein CAPG gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100575G2, Actin Regulatory Protein CAPG gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100575G3, Actin Regulatory Protein CAPG gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256139, NM_001256140, NM_001320732, NM_001320733, NM_001320734, NM_001747
• Synonyms: AFCP; HEL-S-66; MCP
• Summary: 'This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]'