Human CBR3 activation kit by CRISPRa

CAT#: GA100616

CBR3 CRISPRa kit - CRISPR gene activation of human carbonyl reductase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CBR3
• Locus ID: 874
• Kit Components:

  GA100616G1, CBR3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100616G2, CBR3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100616G3, CBR3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001236
• Synonyms: hCBR3; HEL-S-25; SDR21C2
• Summary: 'Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008]'