Human CD3G activation kit by CRISPRa

CAT#: GA100645

CD3G CRISPRa kit - CRISPR gene activation of human CD3g molecule

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CD3G
• Locus ID: 917
• Kit Components:

  GA100645G1, CD3G gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100645G2, CD3G gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100645G3, CD3G gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000073
• Synonyms: CD3-GAMMA; IMD17; T3G
• Summary: 'The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008]'