Human CD40L (CD40LG) activation kit by CRISPRa

CAT#: GA100681

CD40LG CRISPRa kit - CRISPR gene activation of human CD40 ligand

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CD40LG
• Locus ID: 959
• Kit Components:

  GA100681G1, CD40L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100681G2, CD40L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100681G3, CD40L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000074
• Synonyms: CD40L; CD154; gp39; hCD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP
• Summary: 'The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]'