Human LI Cadherin (CDH17) activation kit by CRISPRa

CAT#: GA100728

CDH17 CRISPRa kit - CRISPR gene activation of human cadherin 17

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDH17
• Locus ID: 1015
• Kit Components:

  GA100728G1, LI Cadherin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100728G2, LI Cadherin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100728G3, LI Cadherin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001144663, NM_004063
• Synonyms: CDH16; HPT-1; HPT1
• Summary: 'This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]'