Human CHKL (CHKB) activation kit by CRISPRa

CAT#: GA100800

CHKB CRISPRa kit - CRISPR gene activation of human choline kinase beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CHKB
• Locus ID: 1120
• Kit Components:

  GA100800G1, CHKL gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100800G2, CHKL gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100800G3, CHKL gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005198, NM_152253
• Synonyms: CHETK; CHKL; CK; CKB; CKEKB; EK; EKB; MDCMC
• Summary: 'Choline kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to phosphocholine/phosphoethanolamine. This is the first enzyme in the biosynthesis of phosphatidylcholine/phosphatidylethanolamine in all animal cells. The highly purified CKs from mammalian sources and their recombinant gene products have been shown to have EK activity also, indicating that both activities reside on the same protein. The choline kinase-like protein encoded by CHKL belongs to the choline/ethanolamine kinase family; however, its exact function is not known. Read-through transcripts are expressed from this locus that include exons from the downstream CPT1B locus. [provided by RefSeq, Jun 2009]'