Human CHRNA1 activation kit by CRISPRa

CAT#: GA100811

CHRNA1 CRISPRa kit - CRISPR gene activation of human cholinergic receptor nicotinic alpha 1 subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CHRNA1
• Locus ID: 1134
• Kit Components:

  GA100811G1, CHRNA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100811G2, CHRNA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100811G3, CHRNA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000079, NM_001039523
• Synonyms: ACHRA; ACHRD; CHRNA; CMS1A; CMS1B; CMS2A; FCCMS; SCCMS
• Summary: 'The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2012]'