Human Creatine kinase B type (CKB) activation kit by CRISPRa

CAT#: GA100826

CKB CRISPRa kit - CRISPR gene activation of human creatine kinase B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CKB
• Locus ID: 1152
• Kit Components:

  GA100826G1, Creatine kinase B type gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100826G2, Creatine kinase B type gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100826G3, Creatine kinase B type gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001823, NM_001362531
• Synonyms: B-CK; BCK; CKBB; HEL-211; HEL-S-29
• Summary: 'The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]'