Human CLCN6 activation kit by CRISPRa

CAT#: GA100847

CLCN6 CRISPRa kit - CRISPR gene activation of human chloride voltage-gated channel 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLCN6
• Locus ID: 1185
• Kit Components:

  GA100847G1, CLCN6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100847G2, CLCN6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100847G3, CLCN6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256959, NM_001286, NM_021735, NM_021736, NM_021737, NR_046428
• Synonyms: CLC-6
• Summary: 'This gene encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. This protein is primarily localized to late endosomes and functions as a chloride/proton antiporter. Alternate splicing results in both coding and non-coding variants. Additional alternately spliced variants have been described but their full-length structure is unknown. [provided by RefSeq, Mar 2012]'