Human CLN3 activation kit by CRISPRa

CAT#: GA100858

CLN3 CRISPRa kit - CRISPR gene activation of human CLN3 lysosomal/endosomal transmembrane protein, battenin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLN3
• Locus ID: 1201
• Kit Components:

  GA100858G1, CLN3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100858G2, CLN3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100858G3, CLN3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000086, NM_001042432, NM_001286104, NM_001286105, NM_001286109, NM_001286110, NM_001286105.2, NM_001286109.2, NM_001286110.2, NM_001286104.2
• Synonyms: BTN1; BTS; JNCL
• Summary: 'This gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]'