Human Clathrin light chain (CLTA) activation kit by CRISPRa

CAT#: GA100863

CLTA CRISPRa kit - CRISPR gene activation of human clathrin light chain A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLTA
• Locus ID: 1211
• Kit Components:

  GA100863G1, Clathrin light chain gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100863G2, Clathrin light chain gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100863G3, Clathrin light chain gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001076677, NM_001184760, NM_001184761, NM_001184762, NM_001311203, NM_001311204, NM_001311205, NM_001311206, NM_001833, NM_007096, NR_132349
• Synonyms: LCA
• Summary: 'Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 8 and 12. [provided by RefSeq, May 2010]'