Human Collagen IV (COL4A2) activation kit by CRISPRa

CAT#: GA100898

COL4A2 CRISPRa kit - CRISPR gene activation of human collagen type IV alpha 2 chain

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: COL4A2
• Locus ID: 1284
• Kit Components:

  GA100898G1, Collagen IV gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100898G2, Collagen IV gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100898G3, Collagen IV gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001846
• Synonyms: ICH; POREN2
• Summary: 'This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. The C-terminal portion of the protein, known as canstatin, is an inhibitor of angiogenesis and tumor growth. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jul 2008]'