Human COL12A1 activation kit by CRISPRa

CAT#: GA100917

COL12A1 CRISPRa kit - CRISPR gene activation of human collagen type XII alpha 1 chain

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: COL12A1
• Locus ID: 1303
• Kit Components:

  GA100917G1, COL12A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100917G2, COL12A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100917G3, COL12A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004370, NM_080645
• Synonyms: BA209D8.1; COL12A1L; DJ234P15.1
• Summary: 'This gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]'