Human Ceruloplasmin (CP) activation kit by CRISPRa

CAT#: GA100946

CP CRISPRa kit - CRISPR gene activation of human ceruloplasmin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CP
• Locus ID: 1356
• Kit Components:

  GA100946G1, Ceruloplasmin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100946G2, Ceruloplasmin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100946G3, Ceruloplasmin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000096, NR_046371
• Synonyms: CP-2
• Summary: 'The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012]'