Human Carboxypeptidase A (CPA1) activation kit by CRISPRa

CAT#: GA100947

CPA1 CRISPRa kit - CRISPR gene activation of human carboxypeptidase A1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CPA1
• Locus ID: 1357
• Kit Components:

  GA100947G1, Carboxypeptidase A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100947G2, Carboxypeptidase A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100947G3, Carboxypeptidase A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001868
• Synonyms: CPA
• Summary: This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015]