Human NG2 (CSPG4) activation kit by CRISPRa

CAT#: GA101033

CSPG4 CRISPRa kit - CRISPR gene activation of human chondroitin sulfate proteoglycan 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CSPG4
• Locus ID: 1464
• Kit Components:

  GA101033G1, NG2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101033G2, NG2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101033G3, NG2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001897
• Synonyms: HMW-MAA; MCSP; MCSPG; MEL-CSPG; MSK16; NG2
• Summary: 'A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells. [provided by RefSeq, Jul 2008]'