Human CTBP1 activation kit by CRISPRa

CAT#: GA101051

CTBP1 CRISPRa kit - CRISPR gene activation of human C-terminal binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CTBP1
• Locus ID: 1487
• Kit Components:

  GA101051G1, CTBP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101051G2, CTBP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101051G3, CTBP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001012614, NM_001328
• Synonyms: BARS
• Summary: 'This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]'