Human Cathepsin O (CTSO) activation kit by CRISPRa

CAT#: GA101074

CTSO CRISPRa kit - CRISPR gene activation of human cathepsin O

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CTSO
• Locus ID: 1519
• Kit Components:

  GA101074G1, CTSO gRNA vector 1 in pCas-Guide-CRISPRa

  GA101074G2, CTSO gRNA vector 2 in pCas-Guide-CRISPRa

  GA101074G3, CTSO gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001334
• Synonyms: CTSO1
• Summary: The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase. [provided by RefSeq, Jul 2008]