Human CYP2F1 activation kit by CRISPRa

CAT#: GA101105

CYP2F1 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 2 subfamily F member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYP2F1
• Locus ID: 1572
• Kit Components:

  GA101105G1, CYP2F1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101105G2, CYP2F1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101105G3, CYP2F1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000774, NR_135528
• Synonyms: C2F1; CYP2F; CYPIIF1
• Summary: 'This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]'