Human DCI (ECI1) activation kit by CRISPRa

CAT#: GA101149

ECI1 CRISPRa kit - CRISPR gene activation of human enoyl-CoA delta isomerase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ECI1
• Locus ID: 1632
• Kit Components:

  GA101149G1, DCI gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101149G2, DCI gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101149G3, DCI gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001178029, NM_001919
• Synonyms: DCI
• Summary: 'This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]'