Human DCTD activation kit by CRISPRa

CAT#: GA101152

DCTD CRISPRa kit - CRISPR gene activation of human dCMP deaminase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DCTD
• Locus ID: 1635
• Kit Components:

  GA101152G1, DCTD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101152G2, DCTD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101152G3, DCTD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001012732, NM_001921, NM_001351743, NM_001351744, NM_001351745, NM_001351747, NM_001351748, NM_001351750, NM_001351753
• Synonyms: MGC111062
• Summary: 'The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'