Human GSDME activation kit by CRISPRa

CAT#: GA101189

GSDME CRISPRa kit - CRISPR gene activation of human gasdermin E

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GSDME
• Locus ID: 1687
• Kit Components:

  GA101189G1, GSDME gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101189G2, GSDME gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101189G3, GSDME gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001127453, NM_001127454, NM_004403
• Synonyms: ICERE-1
• Summary: 'Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'