Human PSD93 (DLG2) activation kit by CRISPRa

CAT#: GA101209

DLG2 CRISPRa kit - CRISPR gene activation of human discs large MAGUK scaffold protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DLG2
• Locus ID: 1740
• Kit Components:

  GA101209G1, PSD93 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101209G2, PSD93 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101209G3, PSD93 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142699, NM_001142700, NM_001142702, NM_001206769, NM_001300983, NM_001364, NM_001351274, NM_001351275, NM_001351276
• Synonyms: chapsyn-110; PPP1R58; PSD-93; PSD93
• Summary: 'This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known. [provided by RefSeq, Dec 2008]'