Human ECT2 activation kit by CRISPRa

CAT#: GA101322

ECT2 CRISPRa kit - CRISPR gene activation of human epithelial cell transforming 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ECT2
• Locus ID: 1894
• Kit Components:

  GA101322G1, ECT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101322G2, ECT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101322G3, ECT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001258315, NM_001258316, NM_018098, NM_001349094, NM_001349095, NM_001349096, NM_001349097, NM_001349098, NM_001349099, NM_001349100, NM_001349101, NM_001349102, NM_001349103, NM_001349104
• Synonyms: ARHGEF31
• Summary: 'The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]'