Human Ephrin A2 (EFNA2) activation kit by CRISPRa

CAT#: GA101342

EFNA2 CRISPRa kit - CRISPR gene activation of human ephrin A2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EFNA2
• Locus ID: 1943
• Kit Components:

  GA101342G1, Ephrin A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101342G2, Ephrin A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101342G3, Ephrin A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001405
• Synonyms: ELF-1; EPLG6; HEK7-L; LERK-6; LERK6
• Summary: 'This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008]'