Human EIF4EBP2 activation kit by CRISPRa

CAT#: GA101371

EIF4EBP2 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 4E binding protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EIF4EBP2
• Locus ID: 1979
• Kit Components:

  GA101371G1, EIF4EBP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101371G2, EIF4EBP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101371G3, EIF4EBP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004096
• Synonyms: 4EBP2; PHASII
• Summary: 'This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008]'