Human EIF5 activation kit by CRISPRa

CAT#: GA101374

EIF5 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EIF5
• Locus ID: 1983
• Kit Components:

  GA101374G1, EIF5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101374G2, EIF5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101374G3, EIF5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001969, NM_183004
• Synonyms: EIF-5; EIF-5A
• Summary: 'Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010]'