Human ELF5 activation kit by CRISPRa

CAT#: GA101387

ELF5 CRISPRa kit - CRISPR gene activation of human E74 like ETS transcription factor 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ELF5
• Locus ID: 2001
• Kit Components:

  GA101387G1, ELF5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101387G2, ELF5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101387G3, ELF5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001243080, NM_001243081, NM_001422, NM_198381
• Synonyms: ESE2
• Summary: 'The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]'