Human ELK1 activation kit by CRISPRa

CAT#: GA101388

ELK1 CRISPRa kit - CRISPR gene activation of human ETS transcription factor ELK1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ELK1
• Locus ID: 2002
• Kit Components:

  GA101388G1, ELK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101388G2, ELK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101388G3, ELK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001114123, NM_001257168, NM_005229
• Synonyms: ELK1 protein; ELK1, member of ETS oncogene family; ETS-like gene 1; OTTHUMP00000023224; OTTHUMP00000023225
• Summary: 'This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012]'