Human EN1 activation kit by CRISPRa

CAT#: GA101402

EN1 CRISPRa kit - CRISPR gene activation of human engrailed homeobox 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EN1
• Locus ID: 2019
• Kit Components:

  GA101402G1, EN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101402G2, EN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101402G3, EN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001426
• Synonyms: engrailed homeobox 1; engrailed homolog 1; OTTHUMP00000162091
• Summary: 'Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]'