Human Eph receptor B6 (EPHB6) activation kit by CRISPRa

CAT#: GA101430

EPHB6 CRISPRa kit - CRISPR gene activation of human EPH receptor B6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EPHB6
• Locus ID: 2051
• Kit Components:

  GA101430G1, Eph receptor B6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101430G2, Eph receptor B6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101430G3, Eph receptor B6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001280794, NM_001280795, NM_004445, NR_104001
• Synonyms: HEP
• Summary: 'This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]'