Human XPB (ERCC3) activation kit by CRISPRa

CAT#: GA101448

ERCC3 CRISPRa kit - CRISPR gene activation of human ERCC excision repair 3, TFIIH core complex helicase subunit

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol ERCC3
Locus ID 2071
Kit Components

GA101448G1, XPB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101448G2, XPB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101448G3, XPB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000122, NM_001303416, NM_001303418
Synonyms BTF2; GTF2H; RAD25; TFIIH; TTD2; XPB
Summary 'This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.