Human EYA1 activation kit by CRISPRa

CAT#: GA101490

EYA1 CRISPRa kit - CRISPR gene activation of human EYA transcriptional coactivator and phosphatase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EYA1
• Locus ID: 2138
• Kit Components:

  GA101490G1, EYA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101490G2, EYA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101490G3, EYA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000503, NM_001288574, NM_001288575, NM_172058, NM_172059, NM_172060, NM_001370334, NM_001370335, NM_001370333, NM_001370336
• Synonyms: BOP; BOR; BOS1; OFC1
• Summary: 'This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Dec 2013]'