Human VEGFD activation kit by CRISPRa

CAT#: GA101596

VEGFD CRISPRa kit - CRISPR gene activation of human vascular endothelial growth factor D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VEGFD
• Locus ID: 2277
• Kit Components:

  GA101596G1, VEGFD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101596G2, VEGFD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101596G3, VEGFD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004469
• Synonyms: VEGF-D; VEGFD
• Summary: 'The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011]'