Human FRG1 activation kit by CRISPRa

CAT#: GA101658

FRG1 CRISPRa kit - CRISPR gene activation of human FSHD region gene 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FRG1
• Locus ID: 2483
• Kit Components:

  GA101658G1, FRG1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA101658G2, FRG1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA101658G3, FRG1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004477
• Synonyms: FRG1A; FSG1
• Summary: This gene maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). It is evolutionarily conserved and has related sequences on multiple human chromosomes but DNA sequence analysis did not reveal any homology to known genes. In vivo studies demonstrate the encoded protein is localized to the nucleolus. [provided by RefSeq, Jul 2008]